Gabapentin has what effect on sleep arousals?

Gabapentin has what effect on sleep arousals?

• A. Increases arousals
• B. Decreases arousals
• C. No effect on arousals
• D. Eliminates arousals

Answer: (A)

Gabapentin tends to improve sleep continuity by reducing the brief awakenings that come from motor and sensory activity during sleep. It dampens excitatory neurotransmission through its action on voltage-gated calcium channels, which helps decrease limb movements and related cortical arousals. As a result, the arousal index often goes down and sleep becomes more consolidated. It doesn’t erase arousals completely, and some people may still experience occasional awakenings or daytime sedation as side effects.

Gabapentin tends to improve sleep continuity by reducing the brief awakenings that come from motor and sensory activity during sleep. It dampens excitatory neurotransmission through its action on voltage-gated calcium channels, which helps decrease limb movements and related cortical arousals. As a result, the arousal index often goes down and sleep becomes more consolidated. It doesn’t erase arousals completely, and some people may still experience occasional awakenings or daytime sedation as side effects.